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Reference in Vancouver style Vincken W, Dekhuijzen PNR, Barnes P, on behalf of the ADMIT Group. The ADMIT series - Issues in Inhalation Therapy.
4) How to choose inhaler devices for the treatment of COPD. Prim Care Resp J 2010;19(1):10-20. DOI: http://dx.doi.org/10.4104/pcrj.2009.00062
Citation details Vincken W, Dekhuijzen PNR, Barnes P, on behalf of the ADMIT Group
The ADMIT series - Issues in Inhalation Therapy.
4) How to choose inhaler devices for the treatment of COPD
(2010) Prim Care Resp J 19 (1), pp. 10-20.
DOI: http://dx.doi.org/10.4104/pcrj.2009.00062
Article web page: http://www.thepcrj.org/journ/view_article.php?article_id=668
PDF url: http://www.thepcrj.org/journ/vol19/19_1_10_20.pdf
Abstract:
For patients with COPD, inhalation is the preferred route of administration of respiratory drugs for both maintenance and acute
treatment. Numerous inhaler types and devices have been developed, each with their own particularities, advantages and disadvantages.
Nevertheless, published COPD management guidelines pay little attention to the optimal choice of inhaler devices for COPD patients.
Although efficacy and safety are the primary factors determining the choice of an inhaler device, randomised controlled trials (RCTs)
directly comparing the efficacy and safety of different inhalers in COPD patients are scarce. Systematic reviews on this subject failed to
find significant differences between devices for any of the clinical outcomes studied. When selecting a device for the delivery of inhaled
drugs in 'real life' patients with COPD, other factors should be considered. These include availability and affordability of the inhaled drugs
and inhaler devices, the uniformity of inhaler devices when several drugs are to be inhaled, the ability of patients to handle correctly the
selected device - in particular taking into account the advanced age of the average COPD patient, and finally the patient's preference.
The prescribing clinician's task is to provide comprehensive instructions for correct handling of the device and to review regularly the
patient's inhalation technique.
Keywords: Inhaler devices, inhalation therapy, chronic obstructive pulmonary disease, treatment
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