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Volume 19 Issue 2 June 2010

Original Research

Set-up and pilot of a population cohort for the study of the natural history of COPD and OSA: the PULSAIB study

Pages 140-147
*Joan B Sorianoa, Aina Yáñeza, Feliu Renomb, Mónica de la Peñac, Amalia Gómezd, Rosa Duroe, Ana Uréndezf, Miguel Románf

a Program of Epidemiology and Clinical Research, CIMERA, Fundación Caubet-Cimera Illes Balears, Bunyola, Mallorca, Spain

b Respiratory Unit, Hospital Joan March, Bunyola, Spain

c Respiratory Service, Hospital Universitario Son Dureta, Palma de Mallorca, Spain

d Primary Care, Managment, Palma de Mallorca, Spain

e Atención Primaria, Unidad Básica de Salud de Bunyola, Bunyola, Spain

f Atención Primaria, Centro de Salud de Son Pizà, Palma de Mallorca, Spain

Received 18 September 2009 • Accepted 19 December 2009 • Online 18 February 2010


Abstract
AIMS: We describe the set-up of a population-based study focussed on respiratory conditions, and describe a pilot study – the PULmons SAns Illes Balears (PULSAIB) study – aimed at investigating the natural history of COPD, obstructive sleep apnoea (OSA), and other common chronic diseases. METHODS: A cross-sectional study was designed to survey two fieldwork areas, one rural and one urban, in the Balearic Islands, Spain. Tests conducted included a questionnaire, spirometry with post-bronchodilator (PBD) test, and portable respiratory polygraphy. RESULTS: We assessed all processes and tools to be used, and piloted them in 175 participants from Bunyola (rural) and 130 participants from the Son Pizà area (urban). Within this first cross-sectional assessment of the Balearic population aged 30 to 80 years, we report the prevalence of airflow limitation defined as a PBD FEV1/FVC ratio <0.7 and the prevalence of OSA defined as an apnoea-hypopnoea index (AHI) >10/hour. CONCLUSION: A cohort study in the Balearic population to investigate the natural history of COPD and OSA is feasible.

Keywords
COPD, co-morbidities, general population, natural history, OSA, primary care

* Corresponding author. Joan B Soriano Tel: +34 971 14 84 37 Fax: +34 971 14 84 42 Email: jbsoriano@caubet-cimera.es
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