Volume 20 Issue 4 December 2011 | Research Paper |
|
Community-acquired pneumonia distinguished from
influenza infection based on clinical signs and symptoms
during a novel (swine) influenza A/H1N1 pandemic
Pages 421-426
*Masanori Nakanishia, Yishimasa Yoshidaa, Nobuya Takedab, Hirohumi Hiranab, Takahiro Horitab, Kazuhiko Shimizub, Kazuyuki Hiratanib, Shigeo Toyodab, Takayuki Matsumurab, Eiji Shinnob, Akihiro Hutamurab, Masanari Otab, Toshoki Natazukab
a
Department of Respiratory Medicine, Shinseikai Toyama Hospital, Imizu, Japan
b
Department of Internal Medicine, Shinseikai Toyama Hospital, Imizu, Japan
Received 29 January 2011 • Accepted 2 May 2011 • Online 2 August 2011
Abstract
AIMS: The numbers of patients with influenza-like illnesses increase during influenza outbreaks. A study was undertaken to distinguish
community-acquired pneumonia (CAP) from influenza based on clinical signs and symptoms.
METHODS: This retrospective study investigated patients with positive results in the rapid influenza antigen test and those diagnosed with
CAP during an influenza A/H1N1 pandemic. Significant factors for predicting risk for CAP within 48 hrs from onset and at diagnosis were
selected by multiple regression analysis.
RESULTS: Within 48 hrs of onset and at diagnosis, age and coarse crackles significantly increased the risk of CAP whereas sick contact, sore
throat, and rhinorrhoea significantly decreased the risk of CAP. Duration of illness, sputum, dyspnoea, chest pain, and coarse crackles also
significantly increased the risk of CAP at diagnosis.
CONCLUSIONS: CAP differed somewhat from influenza even within 48 hrs of onset and the differences became even more evident
thereafter.
Cite as: Nakanishi M, Yoshida Y, Takeda N, Hirana H, Horita T, Shimizu K, Hiratani K, Toyoda S, Matsumura T, Shinno E, Hutamura A, Ota M, Natazuka T. Community-acquired pneumonia distinguished from
influenza infection based on clinical signs and symptoms
during a novel (swine) influenza A/H1N1 pandemic. Prim Care Respir J 2011;20(4):421-426. DOI: http://dx.doi.org/10.4104/pcrj.2011.00067
Keywords
Primary care, pulmonary diseases, differential diagnosis, signs, symptoms, community-acquired pneumonia,
influenza A/H1N1
* Corresponding author. Masanori Nakanishi Tel: +81 766 52 2156 Fax: +81 766 52 2197 Email: mnakanishi@nifty.ne.jp | |
